• Francis L. Black


“The simplest of all infectious diseases is measles,” said Kenneth Maxcy 50 years ago.(110) That was before the virus had been isolated or any serological test had become available. The picture is more complicated than Maxcy knew. The virus can persist in humans, at least in defective form, and the distribution of the disease has been made more complex by an artificially determined pattern of vaccine distribution. However, the distinctive clinical response, the durability of immunity, and the absence of both nonhuman hosts and serologically cross-reactive viruses of humans continue to make measles the ideal basic model of infectious disease epidemiology. Essentially every unvaccinated person still contracts measles,(31,43) and most infections are clinically identifiable by an experienced layperson.


Measle Virus Canine Distemper Virus Measle Vaccine Subacute Sclerosing Panencephalitis Measle Case 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Francis L. Black
    • 1
  1. 1.Department of Epidemiology and Public HealthYale University School of MedicineNew HavenUSA

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