Epstein-Barr Virus

  • James C. Niederman
  • Alfred S. Evans


Epstein-Barr virus (EBV), a member of the herpes group of viruses, is the cause of heterophil-positive infectious mononucleosis, of most heterophil-negative cases, and of occasional cases of tonsillitis and pharyngitis in childhood. Rarely, it may involve the liver or central nervous system as primary manifestations. This virus is also implicated as having a causal relationship to African Burkitt lymphoma, B- and T-cell malignant lymphomas, including those in patients with the acquired immunodeficiency syndrome (AIDS), and nasopharyngeal cancer. High antibody titers are present in some patients with sarcoidosis, and in systemic lupus erythematosus.


Chronic Fatigue Syndrome Infectious Mononucleosis Viral Capsid Antigen Acute Viral Infection Clinical Infectious Mononucleosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • James C. Niederman
    • 1
  • Alfred S. Evans
    • 2
  1. 1.Department of Epidemiology and Public HealthYale University School of MedicineNew HavenUSA
  2. 2.Department of Epidemiology and Public HealthYale University School of MedicineNew HavenUSA

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