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Development of Dendritic Cell-Based Genetic Vaccines for Cancer

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Dendritic Cells in Fundamental and Clinical Immunology

Abstract

Cytotoxic T lymphocytes (CTL) are an important component of the host’s immune response to cancer1,2. A number of genes encoding tumor-associated antigens (TAA) and their peptide products which are recognized by CTL in the context of major histocompatibility complex (MHC) class I molecules have recently been identified3,4. Our group has focused on the translation of these new insights into the development and application of novel immunotherapies.

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Tüting, T. et al. (1997). Development of Dendritic Cell-Based Genetic Vaccines for Cancer. In: Ricciardi-Castagnoli, P. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 417. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9966-8_84

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  • DOI: https://doi.org/10.1007/978-1-4757-9966-8_84

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9968-2

  • Online ISBN: 978-1-4757-9966-8

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