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Infection of Human Dendritic Cells by Measles Virus Induces Immune Suppression

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Dendritic Cells in Fundamental and Clinical Immunology

Abstract

Measles is characterized by lifelong immunity and a transient immunosuppression which, in developing countries, is responsible for a high morbidity and a high mortality consecutive to secondary infections. Strickingly, the immune suppression is coincident with MV-specific immunity and continues for several weeks after apparent recovery from measles. The immune suppression is characterized by the loss of delayed-type hypersensitivity skin test responses to recall antigens, such as tuberculin, and by the inhibition of antibody production and cellular immune responses to new antigens (1).

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© 1997 Springer Science+Business Media New York

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Kaiserlian, D., Grosjean, I., Caux, C. (1997). Infection of Human Dendritic Cells by Measles Virus Induces Immune Suppression. In: Ricciardi-Castagnoli, P. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 417. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9966-8_69

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  • DOI: https://doi.org/10.1007/978-1-4757-9966-8_69

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9968-2

  • Online ISBN: 978-1-4757-9966-8

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