Intracellular Sorting of Proteins

  • Claudia Bibus
Part of the NATO ASI Series book series (NSSA, volume 125)

Abstract

Compartmentalization is an essential requirement for cellular function and growth. Each compartment contains a unique set of proteins designed to perform specialized functions, such as oxidative phosphorylation within the mitochondria or ribosome assembly within the nucleolus. How do cells generate and maintain such an asymmetric, highly organized distribution of their proteins? Five major targets of protein transport have been studied in detail: (1) the eukaryotic secretory system; (2) the nucleus; (3) the mitochondria; (4) the chloroplasts; (5) the bacterial secretory system. The scope of this review does not allow in-depth treatment of all important aspects of protein sorting. For detailed reviews see Schekman (1985), Garoff (1985), Farquhar (1985) and Benson et al. (1985).

Keywords

Signal Recognition Particle Mitochondrial Target Sequence Endoplasmic Reti Mitochondrial Import Precursor Polypeptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Claudia Bibus
    • 1
  1. 1.BiocenterUniversity of BaselBaselSwitzerland

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