Controlled Delivery of Nafarelin, An Agonistic Analogue of LHRH, From Microspheres of Poly (D, L Lactic-Co-Glycolic) Acid

  • Lynda M. Sanders
  • Karen M. Vitale
  • Georgia I. Mc Rae
  • Peter B. Mishky
Part of the NATO ASI Series book series (NSSA, volume 125)

Abstract

The present rapid expansion of activity in development of peptide and protein drug compounds has provided a major thrust for development of novel technology for their delivery. These compounds have typically very low oral bioavailability (although this elusive goal is sufficiently attractive for it to remain an active area of exploration).

Keywords

PLGA Microsphere LHRH Agonist Male Rhesus Monkey LHRH Analogue Diffusional Release 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Lynda M. Sanders
    • 1
  • Karen M. Vitale
    • 1
  • Georgia I. Mc Rae
    • 1
  • Peter B. Mishky
    • 1
  1. 1.Syntex ResearchPalo AltoUSA

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