Mechanisms of Injury and Protection in Living Cells and Tissues at Low Temperatures

  • J. Farrant
Part of the The International Cryogenics Monograph Series book series (INCMS)


There is an apparent contradiction between the use of very low temperatures to store isolated cells and tissues for long periods and the experimental finding that living cells are usually destroyed by freezing. It is in understanding ways of overcoming the damage caused by freezing that progress towards the very long-term storage of cells has been achieved.


Cool Rate Sodium Chloride Freezing Point High Solute Concentration Protective Compound 
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Copyright information

© Springer Science+Business Media New York 1970

Authors and Affiliations

  • J. Farrant
    • 1
  1. 1.Clinical Research Centre LaboratoriesNational Institute for Medical ResearchLondonEngland

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