Application of Metabolic Control Analysis to Photosynthesis: the Problem of Getting Data for an Impressive Algorithm

  • Christoph Giersch
  • Dirk Lämmel
  • Klaus Steffen
Part of the NATO ASI Series book series (NSSA, volume 190)


The Mathematics of metabolic control theory is simple, not complicated as could be inferred from the literature. The differential equations describing the time course of metabolite concentrations, and qualitative knowledge of reaction rates allow formulation of two matrices. Control coefficients can then be determined from enzyme elasticities by standard matrix algebra. This procedure is used to calculate symbolically control coefficients of photosynthetic reactions. Also peculiarities of photosynthesis (light-driven reactions, high enzyme concentrations in combination with constraints) that require extension to control theory can be treated by this approach.


Metabolite Concentration Elasticity Matrix Bisphosphate Carboxylase Triose Phosphate Control Coefficient 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Christoph Giersch
    • 1
  • Dirk Lämmel
    • 1
  • Klaus Steffen
    • 2
  1. 1.Institut für Biochemie der PflanzenUniversität DüsseldorfDüsseldorfFederal Republic of Germany
  2. 2.Mathematisches InstitutUniversität DüsseldorfDüsseldorfFederal Republic of Germany

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