Chemical and Non-Chemical Contributions to Breathing in Man, Awake and Asleep
Hypocapnia reproducibly elicits apnoea during anaesthesia in animals and man (Fredericq, 1901; Fink, 1961). However in conscious man during wakefulness there are very variable responses (Douglas and Haldane, 1909; Bainton and Mitchell, 1966). This variability in awake man may be due to behavioural influences upon breathing related to the subjects’ expectations concerning the experiment - which would presumably disappear during sleep. We have therefore examined the effect of sleep onset on the respiratory rhythm during hypocapnia produced by passive mechanical hyperventilation (PMH) during quiet relaxed wakefulness and sleep.
KeywordsSleep Stage Apply Physiology Alpha Rhythm Respiratory Rhythm Nasal Mask
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