Raphe Magnus-Induced Inhibition of Medullary and Spinal Respiratory Activities in the Cat

  • Mamoru Aoki
  • Yoshimi Nakazono


Electrical stimulation of the medullary raphe complex results in significant changes in the discharge patterns of respiratory neurons and phrenic motoneurons. Recent studies by us1, 2 and others3, 4 have demonstrated that stimulation in the nucleus raphe magnus (NRM) produced marked inhibitory effects on respiratory activities in cats and other animals. Previous studies5–7 have also provided evidence for the involvement of several putative transmitter substances such as serotonin (5-hydroxytryptamine) and other transmitters in raphe induced responses.


Electrical Stimulation Phrenic Nerve Chemical Stimulation Unit Discharge Nucleus Raphe Magnus 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Mamoru Aoki
    • 1
  • Yoshimi Nakazono
    • 1
  1. 1.Department of PhysiologySapporo Medical CollegeSapporoJapan

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