Acid Infusion Elicits Thromboxane-Mediated Cardio-Respiratory Effects

  • P. Scheid
  • H. Shams
  • W. Karla
  • J. A. Orr

Abstract

Involvement of peripheral chemoreceptors in the control of respiration is still an open issue. While arterial chemoreceptors are well described, controversy exists about the existence of such receptors in the venous system. During the search in the cat for CO2-sensitive receptors in the larger venous vessels or the right heart, we have intravenously infused 0.25 M HCl, as has been performed in many studies before us. We have, however, observed rather unexpected cardiorespiratory responses which we describe in the following brief review. It compiles the results from a number of studies that we conducted in the cat. For more detailed information about the methodology of each study, we refer the reader to the published papers.

Keywords

Pulmonary Hypertension Vagus Nerve Acid Infusion Respiratory Effect Adult Respiratory Distress Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    J.A. Orr, H. Shams, M.R. Fedde, and P. Scheid, Cardiorespiratory changes during HCl infusion unrelated to decreases in circulating blood pH, J. Appl. Physiol. 62:2362 (1987).PubMedGoogle Scholar
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • P. Scheid
    • 1
  • H. Shams
    • 1
  • W. Karla
    • 1
  • J. A. Orr
    • 2
  1. 1.Institut für PhysiologieRuhr-Universität BochumBochumGermany
  2. 2.Department of Physiology and Cell BiologyUniversity of KansasLawrenceUSA

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