The Ontogeny of the Nervous Control of Cardiovascular Circulation

A Neural Network Model
  • B. Silvano Zanutto
  • Enrique T. Segura
  • Bruno Cernuschi Frias
  • Alberto E. Dams


In adult animals, the nervous system controls the long-term mean blood pressure. The nucleus of the tractus solitarius (NTS) behaves as a comparator between its rostral afferents (the reference) and the cardioreceptor afferents (the feedback). It is hypothesized that, during ontogeny, the nervous system learns the sympathetic efferents from the chemoreceptor feedback. This process is simulated by a neural network model. In a stable metabolism, the model converges to a state in which all the tissues are irrigated with optimal oxygen and carbon dioxide levels.


Neural Network Model Synaptic Weight Discharge Frequency Local Blood Flow Nervous Control 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • B. Silvano Zanutto
    • 1
    • 3
  • Enrique T. Segura
    • 2
  • Bruno Cernuschi Frias
    • 3
  • Alberto E. Dams
    • 4
  1. 1.Department of Psychology: ExperimentalDuke UniversityDurhamUSA
  2. 2.IBYME (CONICET)Buenos AiresArgentina
  3. 3.LIPSIRNFacultad de Ingeniería, Universidad de Buenos AiresBuenos AiresArgentina
  4. 4.Dto ElectronicaFacultad de Ingeniería, Universidad de Buenos AiresBuenos AiresArgentina

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