Spontaneous Replay of Temporally Compressed Sequences by a Hippocampal Network Model

  • D. A. August
  • W. B. Levy


Recent experimental evidence suggests that the hippocampus replays a temporally compressed version of recently-learned spatial sequence information during slow-wave sleep. This phase of sleep is characterized by intermittent episodes of high-frequency firing known as sharp waves. Here we partially characterize a simplified neural network model of hippocampal area CA3, based on integrate-and-fire cells, which is capable of recalling temporally compressed sequence information during brief periods of high activity.


Sharp Wave Recurrent Connection Synaptic Modification Hippocampal Place Cell Oscillatory Local Field Potential 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • D. A. August
    • 1
  • W. B. Levy
    • 1
  1. 1.Department of Neurological SurgeryUniversity of Virginia Health Sciences CenterCharlottesvilleUSA

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