Abstract
Simple integrate-and-fire neurons that accurately reproduce in vitro data from cortical regular spiking cells can display surprisingly sophisticated behavior. To reproduce in vitro f-I plots, voltage after spikes was reset to 5 mV below threshold, and simple spike rate adaptation was added. Small reset results in input sensitivity (high gain) on short time scales; adaptation leads to wide dynamic range over longer time scales. The model displays physiological ISI variability using either delta function or temporally realistic synaptic conductances. Cross correlation between pre- and post-synaptic spikes suggests that cortical neurons may be capable of transmitting information on the millisecond time scale.
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© 1997 Springer Science+Business Media New York
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Troyer, T.W., Miller, K.D. (1997). Integrate-and-Fire Neurons Matched to Physiological F-I Curves Yield High Input Sensitivity and Wide Dynamic Range. In: Bower, J.M. (eds) Computational Neuroscience. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9800-5_32
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DOI: https://doi.org/10.1007/978-1-4757-9800-5_32
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