Biological Effects

  • Leland L. Smith


The high concentration and ubiquitous distribution of cholesterol in human tissues generate concern for the sterol’s function. Searches for function reviewed by Flint in 1862 [779] continue to this day. The role of cholesterol as precursor of bile acids and steroid hormones is clearly established as is also its role in membrane integrity and function, and the association of cholesterol or its esters with several major health afflictions is well demonstrated, such matters as gallstones, hyperlipidemia, atherosclerosis, etc., being prominent. However, a polemic continues to exist regarding whether cholesterol be cause or effect in human disease.


Chapter VIII Sterol Biosynthesis Cholesterol Oxidation Product Exogenous Cholesterol Autoxidation Product 
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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Leland L. Smith
    • 1
  1. 1.The University of Texas Medical BranchGalvestonUSA

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