Distribution of Autoxidation Products
I discuss in this chapter the distribution of cholesterol autoxidation products in Nature and also of their natural occurrence as reported over the years by other investigators. The term “natural occurrence” should pose no difficulties if we retain the obvious meaning of occurrence in Nature, the term conveying no implication of enzymic derivation. Nonetheless, there has accumulated a substantial literature proposing that the common cholesterol autoxidation products found in various tissues be natural products, implication being that these be metabolites formed by enzymic processes in the tissue of origin. It is instructive to review these many reports and the paucity of evidence adduced for this often expressed viewpoint.
KeywordsAutoxidation Product Cyclic Peroxide Marine Brown Alga Ergosterol Peroxide Sterol Derivative
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