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Cholera Enterotoxin (Choleragen)

A Historical Perspective

  • Chapter
Book cover Cholera

Part of the book series: Current Topics in Infectious Disease ((CTID))

Abstract

Slightly over a century ago, during the period from 1883 to 1885, Robert Koch summarized his masterful studies on the etiology of cholera in a series of reports1–8 which presented the first convincing evidence that a particular distinctive microorganism, which he isolated in pure culture and called “comma-bacillus” (now known as Vibrio cholerae O group 1), was:

  1. 1.

    Consistently present during the disease (chiefly in the intestines and the dejecta of the victims)

An important scientific innovation rarely makes its way by gradually winning over and converting its opponents: it rarely happens that Saul becomes Paul. What does happen is that its opponents gradually die out and that the growing generation is familiarized with the idea from the beginning.

Max Planck

The Philosophy of Physics [1936]

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Authors
  1. Richard A. Finkelstein
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Editors and Affiliations

  1. Formerly of the School of Tropical Medicine, Calcutta, India

    Dhiman Barua

  2. Formerly of the Diarrhoeal Diseases Control Programme, World Health Organization, Geneva, Switzerland

    Dhiman Barua

  3. The Johns Hopkins University, Baltimore, Maryland, USA

    William B. Greenough III

  4. Formerly of the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh

    William B. Greenough III

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Finkelstein, R.A. (1992). Cholera Enterotoxin (Choleragen). In: Barua, D., Greenough, W.B. (eds) Cholera. Current Topics in Infectious Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9688-9_8

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