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Genetics

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Cholera

Part of the book series: Current Topics in Infectious Disease ((CTID))

Abstract

The genetic organization of Vibrio cholerae 01 has been investigated by a variety of classical and molecular genetic techniques. The genetic complement of this species includes plasmids, bacteriophage, and insertion sequences; however, all virulence factors so far examined are encoded on a chromosome of ca. 2.8 × 103 kb.1 The basic features of gene structure, transcription, translation, regulation, and genetic exchange are similar to those found in common enteric bacteria, and V. cholerae 01 readily exchanges genetic information via conjugative plasmids with these organisms.2,3

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Authors
  1. James B. Kaper
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  2. Mary M. Baldini
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Editors and Affiliations

  1. Formerly of the School of Tropical Medicine, Calcutta, India

    Dhiman Barua

  2. Formerly of the Diarrhoeal Diseases Control Programme, World Health Organization, Geneva, Switzerland

    Dhiman Barua

  3. The Johns Hopkins University, Baltimore, Maryland, USA

    William B. Greenough III

  4. Formerly of the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh

    William B. Greenough III

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© 1992 Springer Science+Business Media New York

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Kaper, J.B., Baldini, M.M. (1992). Genetics. In: Barua, D., Greenough, W.B. (eds) Cholera. Current Topics in Infectious Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9688-9_4

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  • DOI: https://doi.org/10.1007/978-1-4757-9688-9_4

  • Publisher Name: Springer, Boston, MA

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