Chemists’ Views of Imaging Centers pp 357-366 | Cite as
Solid Phase Reagents in Radiosynthesis
Chapter
Abstract
Radiochemists rely heavily upon functionalized polymers and chromatographic supports for rapid isolation of radiochemicals and labeled intermediates. Extending the use of solid phase reagents from separation steps to radiolabeling reactions and organic transformations has many potential benefits; solid phase methods can shorten overall synthesis times, simplify chemical apparatus, and minimize use of hazardous solvents and reagents. The ability to localize reactions in small columns of functional polymers can also permit easy monitoring and shielding of radiochemical steps.
Keywords
Anion Exchange Resin Resin Column Phase Transfer Catalyst Target Water Acid Site Density
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