Lipocalycins Associated with Mammalian Pheromones
The female golden hamster produces a substance that is emitted in vaginal discharge around the time of estrus and stimulates sexual behavior in male hamsters. This pheromone may be demonstrated in a bioassay using an anesthetized male as a surrogate female, which is placed in the cage of a normal male (Macrides et al., 1984a). If estrous vaginal discharge containing the pheromone is applied to the hindquarters of the surrogate female, a normal male will typically make several intromission attempts consisting of distinct bouts of pelvic thrusting directed at the surrogate female. The number of these bouts can be used as a measure of the activity of the pheromone in vaginal discharge, as demonstrated by a dose-response relation (Macrides et al., 1984b).
KeywordsBank Vole Vaginal Discharge High Molecular Weight Fraction Vomeronasal Organ Major Urinary Protein
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