Action of Sucrose on the Salty Taste Response

  • Keiichi Tonosaki


Taste stimulus adsorption is believed to occur at the taste cell microvillous membrane (Beidler, 1954; Beidler and Tonosaki, 1985). However, little is known about the mechanisms of taste transduction, due mainly to technical difficulties of inserting glass electrodes into mammalian taste cells (Tonosaki and Funakoshi, 1984,1988). We previously reported that the mouse taste cell response to sucrose is a membrane depolarization accompanied by an increase in membrane resistance. The sucrose response increases in amplitude as the membrane is depolarized and decreases in amplitude as the membrane is hyperpolarized. The same taste cell responds to NaCl with membrane depolarization accompanied by a decrease in membrane resistance. The NaCl response increases in amplitude as the membrane is hyperpolarized and decreases in amplitude as the membrane is depolarized. These results suggest that sucrose and NaCl have quite different response generation mechanisms (Tonosaki and Funakoshi, 1988; Tonosaki, 1988).


Membrane Depolarization Taste Receptor Membrane Resistance Taste Cell Taste Stimulus 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Keiichi Tonosaki
    • 1
  1. 1.Department of Oral PhysiologySchool of Dentistry Asahi UniversityHozumi-cho, Motosu-gun GifuJapan

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