Theoretical Calculations of the Electrostatic Potential of Some Tumor Promoters

  • Alastair F. Cuthbertson
  • Derek Higgins
  • Colin Thomson


An understanding of the molecular basis of tumor promotion is essential if we are to fully understand those molecular events which occur between the original initiating step, and the subsequent development of a malignant tumor1,2. It is very likely that the long time period observed for the development of cancer in humans reflects the consequences of exposure to tumor promoters over several years.


Phorbol Ester Indole Alkaloid Molecular Wave Function Diterpene Ester Atom Force Field 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Alastair F. Cuthbertson
    • 1
  • Derek Higgins
    • 1
  • Colin Thomson
    • 1
  1. 1.NFCR Project, Dept. of ChemistryUniversity of St. AndrewsSt. AndrewsScotland

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