Lipid Peroxidation, Protein Thiols, Calcium Homeostasis and Imbalance of Antioxidant Systems in Bromobenzene Induced Liver Damage

  • Alessandro F. Casini
  • Emilia Maellaro
  • Alfonso Pompella
  • Marco Ferrali
  • Mario Comporti


A line of research from our laboratory has been concerned, for several years, with the pathogenetic mechanisms of the liver damage produced by glutathione (GSH)-depleting agents. The present report deals with the main results obtained in in vivo studies with the use of the prototype aryl halide, bromobenzene.


Lipid Peroxidation Calcium Homeostasis Protein Thiol Dehydroascorbic Acid Liver Necrosis 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Alessandro F. Casini
    • 1
  • Emilia Maellaro
    • 1
  • Alfonso Pompella
    • 1
  • Marco Ferrali
    • 1
  • Mario Comporti
    • 1
  1. 1.Istituto di Patologia GeneraleUniversità di SienaSienaItaly

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