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Cytochrome P-450 Function Analyses with Monoclonal Antibodies and cDNA Expression Vectors

  • Harry V. Gelboin
  • Frank J. Gonzalez
  • Sang S. Park
  • Junji Sagara
  • Narayana Battula

Abstract

It is quite fitting and proper to initiate this International Conference devoted to the problems of chemical carcinogenesis with a discussion of the role and function of cytochrome P-450. Cytochrome P-450 is the enzymatic interface between mammalian organisms, including man, and a large variety of foreign chemicals, i.e. xenobiotics, which include almost all chemical carcinogens.

Keywords

Aniline Hydroxylase cDNA Expression Vector Microsomal Monooxygenase System Aniline Hydroxylation Drug Nifedipine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Harry V. Gelboin
    • 1
  • Frank J. Gonzalez
    • 1
  • Sang S. Park
    • 1
  • Junji Sagara
    • 1
  • Narayana Battula
    • 1
  1. 1.Laboratory of Molecular CarcinogenesisNational Cancer Institute, National Institutes of HealthBethesdaUSA

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