Selective Proteolytical Cleavage of the Ligand-Binding Chains of the IL-2-Receptor and IL-6-Receptor by Neutrophil-Derived Proteases

  • U. Bank
  • D. Reinhold
  • D. Kunz
  • S. Ansorge
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 421)


Soluble forms of usually membrane bound molecules were identified in blood or other body fluids. Among these soluble forms of membrane proteins, which have been found to lack the transmembrane and the intracellular domain, the soluble cytokine receptors are of interest, because they have been found to be capable of binding the ligand and of influencing the biological activity of the cytokines1,2.


Acute Pancreatitis Serine Protease U937 Cell Cytokine Receptor Human Neutrophil Elastase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • U. Bank
    • 1
  • D. Reinhold
    • 1
  • D. Kunz
    • 2
  • S. Ansorge
    • 1
  1. 1.Institute of Experimental Internal MedicineCenter of Internal MedicineMagdeburgGermany
  2. 2.Institute of Clinical ChemistryOtto-von-Guericke-University MagdeburgMagdeburgGermany

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