Chloride-Mediated Feedforward Inhibition Is Not Involved in Long-Term Potentiation

  • B. P. C. Melchers
  • W. J. Wadman
  • L. J. Zijp
  • F. H. Lopes da Silva

Abstract

Long-term potentiation (LTP) can be defined as a semipermanent increase in synaptic efficacy that can be induced by tetanic stimulation of afferents. The cellular mechanisms underlying LTP are still unclear. Both presynaptic (Dolphin et al., 1982; Lynch et al., 1985) and postsynaptic (Lynch and Baudry, 1984) changes correlated with LTP have been reported.

Keywords

Test Stimulus Granular Cell Recording Site Dendritic Tree Population Spike 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • B. P. C. Melchers
    • 1
  • W. J. Wadman
    • 1
  • L. J. Zijp
    • 1
  • F. H. Lopes da Silva
    • 1
  1. 1.Department of General ZoologyUniversity of AmsterdamAmsterdamThe Netherlands

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