Conservation of Cellular Mechanisms for Models of Learning and Memory
Obvious differences in the behavioral phenomenology of various learning preparations necessitate differences in underlying brain structure, the number and complexity of responsible neural networks, and the actual transformations and integration of information. The usefulness of a learning model must, therefore, be narrowly defined by real similarities between the model and what is modeled. Dissimilarities will aid discrimination of freewheeling speculation from candidate mechanisms conserved during the course of evolution. A model, whether it be a mathematical description or a close behavioral parallel between one species and another, approaches uniqueness as more and more constraints are satisfied. The value of an interspecies model also depends on the degree to which physiology is conserved during evolution.
KeywordsCellular Mechanism Classical Conditioning Hippocampal Slice Associative Learning Pavlovian Conditioning
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