Pharmacotherapy of Insomnia

  • Edward J. Stepanski
  • Frank J. Zorick
  • Thomas Roth
Part of the Critical Issues in Psychiatry book series (CIPS)


For the purposes of this chapter, “hypnotic medication” is synonymous with “benzodiazepine sedative—hypnotics.” In our opinion, there is almost never an indication to use an older, nonbenzodiazepine hypnotic (e.g., barbiturates, chloral hydrate, glutethimide, meprobamate) for the treatment of insomnia. In situations where depression or nonrestorative sleep syndrome (alpha—delta sleep) is present, the use of a sedating tricyclic antidepressant may be indicated. This will be discussed later.


Anxiety Disorder Sleep Disorder Borderline Personality Disorder Sleep Hygiene Chronic Insomnia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Recommended Readings

  1. Greenblatt, D. J., Shader, R. I., Divoll, M., Harmatz, J. S. (1981). Benzodiazepines: A summary of pharmokinetic properties. British Journal of Clinical Pharmacology, 11, 11S - 16S. This paper describes the pharmokinetics of various benzodiazepine medications. Special emphasis is given to single-dose effects as opposed to multiple-dose effects, and the specific differences between drugs are discussed.Google Scholar
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Edward J. Stepanski
    • 1
  • Frank J. Zorick
    • 1
  • Thomas Roth
    • 1
  1. 1.Sleep Disorders and Research CenterHenry Ford HospitalDetroitUSA

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