Carbonylation pp 173-189 | Cite as

Synthesis of Lactones

  • H. M. Colquhoun
  • D. J. Thompson
  • M. V. Twigg


Lactones are often obtained by carbonylation reactions closely related to the acyclic ester syntheses described in the previous chapter. Although only limited data are available for carbonylative routes to four- and six-membered lactone rings, the preparation of five-membered (γ) lactones has been one of the most intensively studied areas of carbonylation chemistry in recent years. Palladium catalysis in particular has provided a number of extremely clean and facile syntheses, including routes to a wide range of α-methylene-γ-lactones.


Cobalt Catalyst Styrene Oxide Oxidative Carbonylation Allylic Alcohol Propargylic Alcohol 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • H. M. Colquhoun
    • 1
  • D. J. Thompson
    • 2
  • M. V. Twigg
    • 3
  1. 1.ICI Chemicals and Polymers Ltd.RuncornEngland
  2. 2.ICI Specialty ChemicalsWilmingtonUSA
  3. 3.European Vinyls Corporation InternationalBrusselsBelgium

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