Abstract
Ocular melanomas are rare tumors1 (annual incidence of 0.7/100 000 in the USA), which occur in adults close to 60 years old. They arise in the choroïd (Fig.1), which is the ocular vascular tunique, mostly in the eye fundus or, to a lesser extent, in the ciliary body2.
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References
L.E. Zimmerman, Malignant melanoma of the uveal tract, in “Ophtalmie Pathology”, W.H. Spencer, ed.. J.B. Lippincott Co., Philadelphia, 1986, pp. 2072–2139.
J.A. Sahel, J.D. Earle, D.M. Albert, Intraocular melanomas, in “Cancer, Principles and Practice of Oncology, 4th edition,” V.T. De Vita Jr., S. Hellman, S.A. Rosenberg, J.B. Lippincott Co., Philadelphia, 1993, pp. 1662–1678.
I.W. Mc Lean, W.D. Foster, L.E. Zimmerman, Uveal melanoma: Location, size, cell type and enucleation as risk factors in metastasis. Hum. Pathol. 13: 123–132, 1981.
E.S. Gragoudas, K.M. Egan, J.M. Seddon, R.J. Glynn, S.M. Walsh, S.M. FinnJ.E. Munzenrider, M.D. Spar, Survival of patients with metastases from uveal melanoma. Ophtalmologs’, 3: 383–389, 1991.
R.G. Fairchild, New radiotherapeutic techniques in nuclear ophtalmology. Semin. Nuc/. Med.. 14: 35–45, 1984.
J.P. Pignol, L. Meyer, A. Methlin, J.P. Wagner, J.C. Abbe, J. Sahel, Radiothérapie des mélanomes oculaires: Bases physiques et radiobiologiques, techniques actuelles et perspectives d’avenir. Bull. Cane., 81: 127–142, 1994.
S. Packer, J. Coderre, S. Saraf, R.G. Fairchild, J. Hansrote, H. Perry, Boron neutron capture therapy of anterior chamber melanoma with p-boronophenylalanine. Invest. Ophtalmol. Ps. Sci., 33: 395–403, 1992.
J.A. Coderre, J.D. Glass, R.G. Fairchild, U. Roy, S. Cohen, I. Fand, Selective targeting of boronophenylalanine to melanoma in BALB/c mice for neutron capture therapy. Cancer Res., 47: 6377–6383, 1987.
D. Gabel, H. Holstein, B. Larsson, L. Gille, G. Ericson, D. Sacker, P. Som, R.G. Fairchild, Quantitative neutron capture radiography for studying the biodistribution of tumor-seeking boron-containing compounds. Cancer Res., 47: 5451–5454, 1987.
J.P. Pignol, J.C. Abbe, O. Lefebvre, G. Stampfler, A. Methlin, J. Sahel, Thérapie par capture de neutrons des mélanomes oculaires: approche de la dosimétrie et de la microdosimétrie liée à la distribution tissulaire et cellulaire de la 10B-boronophénylalanine. C. R. Acad. Sci., 317: 543–548, 1994.
J.A. Coderre, J.D. Glass, R.G. Fairchild, P.L. Micca, J. Kalef-Ezra, Boronophenylalanine for neutron capture therapy of melanoma. Strahl. Onkol., 165: 215–217, 1989.
J.A. Coderre, J.D. Glass, R.G. Fairchild, P.L. Micca, I. Fand, D.D. Joel, Selective delivery of boron by the melanin precursor analog p-boronophenylalanine to tumors other than melanoma. Cancer Res., 50: 138–141, 1990.
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© 1996 Springer Science+Business Media New York
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Pignol, J.P., Chauvel, P., Abbe, J.C. (1996). Boron Neutron Capture Therapy of Uveal Melanoma. In: Mishima, Y. (eds) Cancer Neutron Capture Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9567-7_89
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DOI: https://doi.org/10.1007/978-1-4757-9567-7_89
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