Measurements of Depth-Dose Distributions in a Phantom for Gadolinium Neutron Capture Therapy

  • Tetsuo Matsumoto
  • Akira Tsuruno

Abstract

The isotope gadolinium (157Gd) has been suggested as an alternative neutron capture therapy (NCT) agent to 10B (1). In a previous communication, we reported the radiation effect of Gd neutron capture reactions in cultured Chinese hamster cells (2). We also presented the calculation results of the depth-dose distributions for neutrons, gamma-rays and internal conversion electrons using the Musashi thermal neutron beam (3). In this paper, the depth-dose distributions for thermal neutron flux, capture gamma ray and internal conversion electron dose rates have been measured in a cylindrical phantom with a simulated tumor containing Gd in terms of Gd concentration, neutron beam size and tumor site.

Keywords

Thermal Neutron Neutron Beam Thermal Neutron Flux Gold Foil Simulated Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    J.A. Shih and R.M. Brugger, “Gadolinium as a neutron capture therapy agent”, Progress in Neutron Capture Therapy for Cancer, B.J.Allen et al. eds., Plenum Press, New York (1992)Google Scholar
  2. 2.
    Y.Akine, N.Tokita, T.Matsumoto, O.Oyama and O.Aizawa, “Gadolinium neutron capture reactions: A radiobiological assay”, Progress in Neutron Capture Therapy for Cancer, B.J.Allen et al. eds., Plenum Press, New York (1992)Google Scholar
  3. 3.
    Tetsuo Matsumoto “Evaluation of the depth-dose distributions for gadolinium neutron capture therapy” in Advance in Neutron Capture Therapy. A. H. Soloway et al. eds. Plenum Press, New York (1993)Google Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Tetsuo Matsumoto
    • 1
  • Akira Tsuruno
    • 2
  1. 1.Atomic Energy Research LaboratoryMusashi Institute of TechnologyKawasaki-shi, 215Japan
  2. 2.Tokai Research Establishment, JAERIIbaraki-ken, 319-11Japan

Personalised recommendations