High-Intensity Fission-Converter-Based Epithermal Neutron Beam for Neutron Capture Therapy

  • Otto K. Harling
  • W. Steadman KigerIII


Some results from a neutronic design study of a fission-converter-based epithermal beam for neutron capture therapy at the 5 MW MIT Research Reactor are presented. It is shown that a high-intensity beam, with ~1010 epithermal neutrons/cm2-s and low background\(\widetilde < \)2×10−11 cGy-cm2 of fast neutrons or gamma rays can be implemented at the Massachusetts Institute of Technology Research Reactor (MITR-II). This beam is capable of delivering single-fraction treatments in a few minutes. The fission-converter concept appears to be well suited to research reactors with large area thermal neutron sources of \(\widetilde < \)0.5 m2 and \(\widetilde < \)1011 n/cm2-s. There are a relatively large number of potentially suitable reactors worldwide, e.g. in the USA there are more than 15 suitable reactors.


Fast Neutron Research Reactor Boron Neutron Capture Therapy Epithermal Neutron Neutron Dose 
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  1. 1.
    H. Rief, R. Van Heusden, and G. Perlini. Generating epithermal neutron beams 1òr neutron capture therapy in small reactors, in: “Advances in Neutron Capture Therapy,” A. H. Soloway, R. F. Barth, and D. E. Carpenter, eds., Plenum Press, New York, 1993, pp. 85–88.CrossRefGoogle Scholar
  2. 2.
    H. Rief, private communication.Google Scholar
  3. 3.
    J.F. Briesmeister, ed, MCNP - A General Monte Carlo N-Particle 7ransporl Code (Version 4A), Los Alamos National Laboratory, LA-12625 (1993).Google Scholar
  4. 4.
    I. Auterinen and P. Hiismaki, “Design of an epithermal neutron beam for the Triga reactor at Otaniemi,” Proceedings of the CLINCT BNCT Workshop, Helsinki, TKK-F-A718, 1993, pp. 14–24.Google Scholar
  5. 5.
    S.D. Clement, J.R. Choi, R.G. Zamenhof, J.C. Yanch, and O.K. Harling, Monte Carlo methods of neutron beam design for neutron capture therapy at the MIT Research Reactor (MITR-Il), in: “Neutron Beam Design, Development, and Performance for Neutron Capture Therapy,” O.K. Harling, J.A. Bernard, and R.G. Zamenhof, eds., Plenum Press, New York, 1989, pp. 51–69.Google Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Otto K. Harling
    • 1
  • W. Steadman KigerIII
    • 1
  1. 1.Nuclear Reactor LaboratoryMassachusetts Institute of TechnologyCambridgeUSA

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