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Normal Tissue Tolerance and Fractionation Effects in Dogs of Boron Neutron Capture Irradiation with Borocaptate Sodium (BSH)

  • Katharina H. I. Philipp
  • René Huiskamp
  • Juan Casado
  • Ray L. Moss

Abstract

In conventional external beam radiation therapy of intracranial high grade gliomas the dose that can be delivered to the tumor is limited by the tolerance of adjacent normal brain. Boron neutron capture therapy (BNCT) theoretically allows the selective delivery of high linear energy transfer (LET) radiation to brain tumors while at the same time sparing surrounding normal brain tissue.

Keywords

Linear Energy Transfer Boron Neutron Capture Therapy Relative Biological Effectiveness Epithermal Neutron Magnetic Resonance Imaging Change 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Katharina H. I. Philipp
    • 1
  • René Huiskamp
    • 1
  • Juan Casado
    • 2
  • Ray L. Moss
    • 2
  1. 1.Department of Radiation TechnologyNetherlands Energy Research FoundationNetherlands
  2. 2.Joint Research CenterPettenThe Netherlands

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