Development of a Method to Use Boron Neutron Capture Therapy for Diffused Tumours of Liver (Taormina Project)
The research informing this paper is based on the idea to treat, by BNCT, the human liver metastases by neutron irradiation of the organ outside the patient. The program, originally proposed by groups of surgeons and physicists, is supported by I.N.F.N. since 1988*.
The liver, after having been Boron enriched, will be irradiated inside the reactor thermal column, then grafted into the same donor.
The method is described by analysing the main details concerning all inherent problems.
Results concerning survival time during the anhepatic phase as obtained in the swine model, physical quantities defining the reactor facility, details concerning the irradiation position, conditions necessary for a safe treatment, preliminary results on Boron uptake by hepatic tissues in the rat model are given and discussed.
KeywordsHepatic Tissue Boron Neutron Capture Therapy Irradiation Position Boron Compound Irradiation Channel
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