A Reappraisal of Cytotoxic Lymphocytes in Human Tumor Immunology

  • Joseph G. Sinkovics


Extensive work done at the Section of Clinical Tumor Virology and Immunology, Department of Medicine, The University of Texas M. D. Anderson Hospital, from 1968 to 1978 on the cytotoxicity of lymphocytes to cultured human tumor cells is reviewed. The early results and concepts are now reinterpreted in the light of newer knowledge generated worldwide in the past few years. This work is now leading to adoptive immunotherapy of human tumors by reinfusion of activated autologous tumor killer (ATK) lymphocytes expanded by co-administration of T cell growth factor (interleukin 2).


Natural Killer Natural Killer Cell K562 Cell Sarcoma Cell Natural Killer Cell Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Joseph G. Sinkovics
    • 1
    • 2
    • 3
  1. 1.Community Cancer CenterSt. Joseph’s HospitalTampaUSA
  2. 2.University of South Florida College of MedicineTampaUSA
  3. 3.Department of Virology and EpidemiologyBaylor College of MedicineHoustonUSA

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