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Cancer and Nutrition pp 211–220Cite as

Dietary Fiber and Cancer

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Part of the book series: Human Nutrition ((HUNU,volume 7))

Abstract

Fiber has been defined by Paul and Southgate (1978) as “the sum of the polysaccharides and lignin which are not digested by the endogenous secretions of the human gastrointestinal tract. This fraction has a variable composition as it is made up of several different types of polysaccharides (pectic substances, hemicelluloses, and celluloses) and the non-carbohydrate lignin.” The description of fiber has been expanded to include plant gums, mucilages, and algal polysaccharides. It is convenient to classify these substances into insoluble fiber (cellulose, hemicellulose, lignin), which decreases intestinal transit time and increases fecal bulk, and soluble fiber (pectic substances, gums), which delays gastric emptying.

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References

  • Armstrong, B., and Doll, R., 1975, Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices, Im . J. Cancer 15: 617–631.

    Article  CAS  Google Scholar 

  • Barbolt, T. A., and Abraham, R., 1978, The effect of bran in dimethylhydrazine-induced colon carcinogenesis in the rat, Proc. Soc. Exp. Biol. Med. 157: 656–659.

    Article  CAS  Google Scholar 

  • Barbolt, T. A., and Abraham, R., 1980, Dose—response, sex differences and the effect of bran in dimethylhydrazine-induced intestinal carcinogenesis in rats, Toxicol. Appl. Pharmacol. 55: 417–422.

    Article  CAS  Google Scholar 

  • Bauer, H. G., Asp, N. G., Oste, R., Dahlqvist, A., and Fredlund, P. E., 1979, Effect of dietary fiber on the induction of colorectal tumors and fecal glucuronidase activity in the rat, Cancer Res. 39: 3752–3756.

    CAS  Google Scholar 

  • Burkitt, D. P., 1971, Epidemiology of cancer of the colon and rectum, Cancer 28: 3–13.

    Article  CAS  Google Scholar 

  • Byers, T., 1988, Diet and cancer. Any progress in the interim? Cancer 62: 1713–1724.

    Article  CAS  Google Scholar 

  • Byers, T., and Graham, S., 1984, The epidemiology of diet and cancer, Adv. Cancer Res. 41: 1–69.

    Article  CAS  Google Scholar 

  • Cleave, T. L., 1956, The neglect of natural principles in current medical practice, J. Roy. Nay. Med. Serv. 42: 55–82.

    Google Scholar 

  • Committee on Diet, Nutrition and Cancer, 1982, Diet, nutrition and cancer, National Academy Press, Washington, DC.

    Google Scholar 

  • Cummings, J. H., and Bingham, S. A., 1987, Dietary fibre, fermentation and large bowel cancer, Cancer Surveys 6: 601–621.

    CAS  Google Scholar 

  • Eastwood, M. A., and Hamilton, D., 1968, Studies on the adsorption of bile salts to non-absorbed components of diet, Biochim. Biophys. Acta 152: 165–173.

    Article  CAS  Google Scholar 

  • Glober, G. A., Nomura, A., Kamiyama, S., Shimoda, A., and Abba, B. C., 1977, Bowel transit time and stool weight in populations with different colon cancer risks, Lancet 2: 110.

    Article  CAS  Google Scholar 

  • Gregor, O., Toman, R., and Prusova, F., 1969, Gastrointestinal cancer and nutrition, Gut 10: 1031–1034.

    Article  CAS  Google Scholar 

  • Hagopian, H. K., Riggs, M. G., Swartz, L. A., and Ingram, V. M., 1977, Effect of n-butyrate on DNA synthesis in chick fibroblasts and HeLa cells, Cell 12: 855–860.

    Article  CAS  Google Scholar 

  • Hakama, M., and Saxen, E. A., 1967, Cereal consumption and gastric cancer, Int. J. Cancer 2: 265–268.

    Article  CAS  Google Scholar 

  • Heaton, K. W., Emmett, P. M., Henry, C. L., Thornton, J. R., Manhire, A., and Hartog, M., 1983, Not just fibre: the nutritional consequences of refined carbohydrate foods, Hum. Nutr. Clin. Nutr. 37C: 31–35.

    CAS  Google Scholar 

  • Higginson, J., and Oettle, A. G., 1960, Cancer incidence in the Bantu and “Cape Coloured” races of South Africa: Report of a cancer survey in the Transvaal, J. Natl. Cancer Inst. 24: 589–671.

    CAS  Google Scholar 

  • Hill, M. J., Drasar, B. S., Aries, V. C., Crowther, J. S., Hawksworth, G., and Williams, R. E. O., 1971, Bacteria and the aetiology of cancer of the large bowel, Lancet 1: 95–100.

    Article  CAS  Google Scholar 

  • Hill, M. J., Maclennan, R., and Newcombe, K., 1979, Diet and large bowel cancer in three socioeconomic groups in Hong Kong, Lancet 1: 436.

    Article  CAS  Google Scholar 

  • Jacobs, L. R., 1983, Enhancement of rat colon carcinogenesis by wheat bran consumption during the stage of 1,2-dimethylhydrazine administration, Cancer Res. 43: 4057–4061.

    CAS  Google Scholar 

  • Jacobs, L. R., 1986, Modification of experimental colon carcinogenesis by dietary fibers, Adv. Exp. Biol. Med. 206: 105–118.

    CAS  Google Scholar 

  • Jensen, O. M., Maclennan, R., and Wahrendorf, J., 1982, Diet, bowel function, fecal characteristics and large bowel cancer in Denmark and Finland, Nutr. Cancer 4: 5–19.

    Article  CAS  Google Scholar 

  • Kassira, E., Parent, L., and Vahouny, G. V., 1976, Colon cancer. An epidemiological survey, Am. J. Dig. Dis. 21: 205–214.

    Article  CAS  Google Scholar 

  • Kelsay, J. L., Behall, K. M., and Prather, E. S., 1978, Effect of fiber from fruits and vegetables on metabolic responses of human subjects. 1. Bowel transit time, number of defecations, fecal weight, urinary excretions of energy and nitrogen and apparent digestibilities of energy, nitrogen and fat, Am. J. Clin. Nutr. 31: 1149–1153.

    CAS  Google Scholar 

  • Kim, Y. S., Tsao, D., Morita, A., and Bella, A., 1982, Effect of sodium butyrate on three human colorectal adenocarcinoma cell lines in culture, in: Colon Carcinogenesis ( R. A. Malt, and R. C. N. Williamson, eds.), MTP Press, Lancaster, UK, pp. 317–323.

    Google Scholar 

  • Klurfeld, D. M., and Kritchevsky, D., 1986, Dietary fiber and human cancer: Critique of the literature, Adv. Exp. Med. Biol. 206: 119–135.

    CAS  Google Scholar 

  • Klurfeld, D. M., Weber, M. M., and Kritchevsky, D., 1987, Inhibition of chemically induced mammary and colon tumor promotion by caloric restriction in rats fed increased dietary fat, Cancer Res. 47:2759–2762. Kritchevsky, D., 1983, Fiber, steroids and cancer, Cancer Res. 43 (Suppl.): 24915–2495S.

    Google Scholar 

  • Kritchevsky, D., 1985, Dietary fiber and cancer, Nutr. Cancer 6: 213–219.

    Article  Google Scholar 

  • Kritchevsky, D., and Klurfeld, D. M., 1981, Fat and cancer, in: Nutrition and Cancer: Etiology and Treatment ( G. R. Newell and N. M. Ellison, eds.), Raven Press, New York, pp. 173–188.

    Google Scholar 

  • Kritchevsky, D., and Klurfeld, D. M., 1986, Influence of caloric intake on experimental carcinogenesis: A review, Adv. Exp. Med. Biol. 206: 55–68.

    CAS  Google Scholar 

  • Kune, S., Kune, G. A., and Watson, L. F., 1987, Case control study of dietary etiological factors: The Melbourne colorectal cancer study, Nutr. Cancer 9: 21–42.

    Article  CAS  Google Scholar 

  • Lyon, J. L., Mahoney, A. W., West, D. W., Gardner, J. W., Snuth, K. R., Sorenson, A. W., and Stanish, W., 1987, Energy intake: its relationship to colon cancer risk, J. Natl. Cancer Inst. 78: 853–861.

    CAS  Google Scholar 

  • MacDonald, I. A., Webb, G. R., and Mahony, D. E., 1978, Fecal hydroxysteroid dehydrogenase activities in vegetarian Seventh-Day Adventists, control subjects and bowel cancer patients, Am. J. Clin. Nutr. 31: S233–S238.

    CAS  Google Scholar 

  • Manousos, O., Day, N. E., Trichopoulous, D., Gerovassilis, F., Tzonou, A., and Polychronopoulou, A., 1983, Diet and colorectal cancer: A case–control study in Greece, Int. J. Cancer 32: 1–5.

    Article  CAS  Google Scholar 

  • Marquart-Moulin, G., Riboli, E., Cornee, J., Chamay, B., Berthezene, P., and Day, N., 1986, Case-control study on colorectal cancer and diet in Marseilles, Int. J. Cancer 38: 183–191.

    Article  Google Scholar 

  • Nigro, N. D., Bhadrachari, N., and Chonichai, C., 1973, A rat model for studying colonic cancer: effect of cholestyramine on induced tumors, Dis. Colon Rectum 16: 438–443.

    Article  CAS  Google Scholar 

  • Paul, A. A., and Southgate, D. A. T., 1978, McCance and Widdowson’s The Composition of Foods, 4th ed., Elsevier/North-Holland, Biomedical Press, Amsterdam.

    Google Scholar 

  • Pickle, L. W., Greene, M. H., Ziegler, R. G., Toledo, A., Hoover, R., Lynch, H. T., and Fraumeni, J. F., Jr., 1984, Colorectal cancer in rural Nebraska, Cancer Res. 44: 363–369.

    CAS  Google Scholar 

  • Potter, J. D., and McMichael, A. J., 1986, Diet and cancer of the colon and rectum: A case–control study, J. Natl. Cancer Inst. 76: 557–569.

    CAS  Google Scholar 

  • Reddy, B. S., Hedges, A. R., Laakso, K., and Wynder, E. L., 1978, Metabolic epidemiology of large bowel cancer, Cancer 42: 2832–2838.

    Article  CAS  Google Scholar 

  • Reddy, B. S., Maeura, Y., and Wayman, M., 1983, Effect of dietary corn bran and autohydrolyzed lignin on 3,2-dimethyl-4-aminobiphenyl-induced intestinal carcinogenesis in male F344 rats, J. Natl. Cancer Inst. 71: 419–423.

    CAS  Google Scholar 

  • Rogers, A. E., and Longnecker, M. P., 1988, Biology of disease. Dietary and nutritional influences on cancer: A review of epidemiological and experimental data, Lab. Invest. 59: 729–759.

    CAS  Google Scholar 

  • Slattery, M. L., Sorenson, A. W., Mahoney, A. W., French, T. K., Kritchevsky, D., and Street, J. C., 1988, Diet and colon cancer: assessment of risk by fiber type and food source, J. Natl. Cancer Inst. 80: 1474–1480.

    Article  CAS  Google Scholar 

  • Southgate, D. A. T., and Dumin, J. V. G. A., 1970, Caloric conversion factors. An experimental reassessment of the factors used in the calculation of the energy value of human diets, Br. J. Nutr. 24: 517–535.

    Article  CAS  Google Scholar 

  • Stocks, P., and Kam, M. K., 1933, A cooperative study of the habits, homelife, dietary and family histories of cancer patients and an equal number of control patients, Ann. Eugen (London) 5: 237–280.

    Article  Google Scholar 

  • Story, J. A., and Kritchevsky, D., 1976, Comparison of the binding of various bile acids and bile salts by several types of fiber, J. Nutr. 106: 1292–1294.

    CAS  Google Scholar 

  • Tuyns, A. J., 1986, A case-control study on colorectal cancer in Belgium: Preliminary results, Med. Sociale Preventive 31: 81–82.

    Article  CAS  Google Scholar 

  • Walker, A. R. P., Walker, B. F., and Walker, A. J., 1986, Faecal pH, dietary fibre intake and proneness to colon cancer in four South African populations, Br . J. Cancer 53: 489–495.

    Article  CAS  Google Scholar 

  • Watanabe, K., Reddy, B. S., Wong, C. Q., and Weisburger, J. H., 1978, Effect of dietary undegraded carageenan on colon carcinogenesis in F344 rats treated with azoxymethane or methylnitrosourea, Cancer Res. 38: 4427–4430.

    CAS  Google Scholar 

  • Willett, W. C., and MacMahon, B., 1984, Diet and cancer—An overview, N. Engl. J. Med. 310: 633–638, 697–703.

    Article  Google Scholar 

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Authors and Affiliations

  1. The Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania, 19104, USA

    David Kritchevsky & David M. Klurfeld

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  1. David Kritchevsky
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  2. David M. Klurfeld
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Editors and Affiliations

  1. Schools of Public Health and Medicine, University of California, Los Angeles, Los Angeles, California, USA

    Roslyn B. Alfin-Slater

  2. The Wistar Institute, Philadelphia, Pennsylvania, USA

    David Kritchevsky

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Kritchevsky, D., Klurfeld, D.M. (1991). Dietary Fiber and Cancer. In: Alfin-Slater, R.B., Kritchevsky, D. (eds) Cancer and Nutrition. Human Nutrition, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9561-5_10

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  • DOI: https://doi.org/10.1007/978-1-4757-9561-5_10

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