Summary of Workshop
Immunity to and Vaccines for Campylobacters
Chapter
Abstract
After campylobacters were discovered to be a major cause of human diarrhoeal disease, there was a flurry of studies to characterize the immune response to these organisms. These studies, previously reviewed,6,7,11,15,16,17,19,22 primarily concentrated on the quality of the antibody response, the diagnostic and epidemiologic value of assaying for antibodies and the specificity of those antigens expressed by campylobacters which elicit such humoral responses. Similar work continues today as new Campylobacter species, like C.concisus, are discovered (Zhi et al., 4–28). Previous reviews suggest that the cell-mediated aspects of immunity to campylobacters have been largely unstudied and it seems to have been generally assumed that antibodies are the likely predominant means of immune clearance and, presumably, immunologically-mediated protection.
Keywords
Future Trend Subunit Vaccine Flagellin Gene Predominant Means Complex Vaccine
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