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Migration and Proliferation of Mononuclear Phagocytes in the Central Nervous System

  • Chapter
Brain Plasticity

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 429))

Abstract

Microglia are resident CNS cells expressing markers of mononuclear phagocytes (Perry, 1994a). Transformation of the microglial phenotype is a hallmark of CNS injuries. This process defined as microglial activation was described in virtually all human neuropathologies, including neurodegenerative diseases, multiple sclerosis and HIV infection (Dickson et al., 1993; McGeer et al., 1993; Kreutzberg 1996).

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Authors and Affiliations

  1. INSERM U.114, Chaire de Neuropharmacologie, Collège de France, 11 Place Marcelin Berthelot, 75231, Paris Cedex 05, France

    Michel Mallat, Charles-Félix Calvo & Alexandre Dobbertin

Authors
  1. Michel Mallat
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  2. Charles-Félix Calvo
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  3. Alexandre Dobbertin
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Editor information

Editors and Affiliations

  1. University of Torino, Torino, Italy

    Guido Filogamo

  2. University of Colorado Health Sciences Center, Denver, Colorado, USA

    Antonia Vernadakis

  3. University of Cagliari, Cagliari, Italy

    Fulvia Gremo

  4. Université Montpellier II, Montpellier, France

    Alain M. Privat

  5. University of California, Berkeley, California, USA

    Paola S. Timiras

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Mallat, M., Calvo, CF., Dobbertin, A. (1997). Migration and Proliferation of Mononuclear Phagocytes in the Central Nervous System. In: Filogamo, G., Vernadakis, A., Gremo, F., Privat, A.M., Timiras, P.S. (eds) Brain Plasticity. Advances in Experimental Medicine and Biology, vol 429. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9551-6_7

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