General Methods

  • Robert Thompson
  • Francis M. Crinella
  • Jen Yu
Part of the Critical Issues in Neuropsychology book series (CINP)


Weanling (21- to 25-day-old) male Sprague—Dawley albino rats, 50–65 g, underwent surgery under deep chloral hydrate anesthesia (400 mg/kg). Cortical lesions were accomplished by aspiration, while all subcortical lesions were made stereotaxically by passing a constant anodal current of 1.0–2.5 mA for a duration of 5–10 sec through an implanted stainless steel electrode (0.5 mm in diameter) with 0.5–1.0 mm of the tip exposed. Sham-operated control animals underwent the same surgical procedure as the experimental animals, except for the drilling of the skull and the insertion of the suction tip or lesion electrode into the brain.


Preliminary Training Subcortical Lesion Choice Chamber Black Card Maze Problem 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Robert Thompson
    • 1
  • Francis M. Crinella
    • 2
  • Jen Yu
    • 3
  1. 1.Late of University of California IrvineIrvineUSA
  2. 2.State Developmental Research InstitutesCosta MesaUSA
  3. 3.University of California IrvineIrvineUSA

Personalised recommendations