Low Resolution Model of Botulinum Neurotoxin Type A

  • Raymond C. Stevens


The function of botulinum neurotoxin is rapidly being elucidated by biochemical and molecular biology techniques. Although this information is critical to understanding the function of the toxin, the 3-dimensional structure of the neurotoxin is necessary to correlate the structure and function. To better understand the function of botulinum neurotoxin, the three-dimensional structure determination of the neurotoxin is being undertaken using the technique of X-ray diffraction. The technique of dynamical light scattering is being used to aid the crystallographic investigation of the 3-dimensional structure determination of serotype A.


Dynamical Light Scattering Diphtheria Toxin Molecular Biology Technique Botulinum Neurotoxin Clostridium Botulinum 
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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Raymond C. Stevens
    • 1
  1. 1.Department of Chemistry Gibbs Chemical LaboratoryHarvard UniversityCambridgeUSA

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