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Kell Blood Group System and the McLeod Syndrome

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Molecular Basis of Human Blood Group Antigens

Part of the book series: Blood Cell Biochemistry ((BLBI,volume 6))

Abstract

The Kell blood group system was named after the person who made the first recognized antibody. Other than ABO, the Kell antigens are perhaps only second to the D antigen in the Rh system as potent immunogens. About 5% of K:−1 persons who are transfused with a single unit of K:1 red cells make anti-K1 IgG. The Kell blood group system is important not only in transfusion but also clinically since K1 is present on red cells of fetuses and maternal alloimmunization may cause hemolytic disease in the newborn.

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Authors and Affiliations

  1. Department of Biochemistry, Lindsley F. Kimball Research Institute, The New York Blood Center, New York, New York, 10021, USA

    Colvin M. Redman & Soohee Lee

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  1. Colvin M. Redman
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  2. Soohee Lee
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Editors and Affiliations

  1. National Institute of Blood Transfusion, Paris, France

    Jean-Pierre Cartron  & Philippe Rouger  & 

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Redman, C.M., Lee, S. (1995). Kell Blood Group System and the McLeod Syndrome. In: Cartron, JP., Rouger, P. (eds) Molecular Basis of Human Blood Group Antigens. Blood Cell Biochemistry, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9537-0_7

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  • DOI: https://doi.org/10.1007/978-1-4757-9537-0_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-44853-9

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