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Molecular Basis of Human Blood Group Antigens pp 37–73Cite as

ABO, Hh, Lewis, and Secretion

Serology, Genetics, and Tissue Distribution

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Part of the book series: Blood Cell Biochemistry ((BLBI,volume 6))

Abstract

ABO, the major red cell alloantigen system, was discovered by Landsteiner (1901) testing the agglutination of normal erythrocytes by serum from different individuals. His tests showed that individuals with A antigen on erythrocytes have anti-B antibodies in serum. People with B antigen on red cells have anti-A in serum. Persons devoid of A and B antigens on red cells (blood group zero or O) have both anti-A and anti-B, and AB individuals with both antigens on red cells have no natural anti-A or anti-B.

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  1. Unité de Recherche U178 de l’Institut National de la Santé et de la Recherche Médicale (INSERM), 94807, Villejuif Cedex, France

    Rafael Oriol

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  1. National Institute of Blood Transfusion, Paris, France

    Jean-Pierre Cartron  & Philippe Rouger  & 

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Oriol, R. (1995). ABO, Hh, Lewis, and Secretion. In: Cartron, JP., Rouger, P. (eds) Molecular Basis of Human Blood Group Antigens. Blood Cell Biochemistry, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9537-0_2

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  • DOI: https://doi.org/10.1007/978-1-4757-9537-0_2

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