Adorini, L., Appella, E., Doria, G., Cardinauz, F., and Nagy, Z. A., 1989, Competition for antigen presentation in living cells involves exchange of peptides bound by class II MHC molecules, Nature (London)
Aiba, S., and Katz, S. I., 1991, The ability of cultured Langerhans cells to process and present protein antigens is MHC-dependent, J. Immunol.
Bakke, O., and Dobberstein, B., 1990, MHC class II-associated invariant chain contains a sorting signal for endosomal compartments, Cell
Bennett, K., Levine, T., Ellis, J. S., Peanasky, R. J., Samloff, I. M., Kay, J., and Chain, B. M., 1992, Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E, Eur J. Immunol.
Besterman, J., Airhart, J. A., Woodworth, R. C., and Low, R. B., 1981, Exocytosis of pinocytosed fluid in cultured cells: Kinetic evidence for rapid turnover and compartmentation, J. Cell Biol.
Bhardwaj, V., and Colston, M. J., 1988, The processing and presentation of mycobacterial antigens by human monocytes, Eur. J. Immunol.
Blum, J. S., and Cresswell, P., 1988, Role for intracellular proteases in the processing and transport of class II HLA antigens, Proc. Natl. Acad. Sci. USA
Brodsky, F. M., and Guagliardi, L., 1991, The cell biology of antigen processing and presentation, Annu. Rev. Immunol.
Buus, S., and Werdelin, 0., 1986, A group specific inhibitor of lysosomal cysteine proteinases selectively inhibits both proteolytic degradation and presentation of the antigen DNP-poly-L-lysine by guinea pig accessory cells to T cells, J. Immunol.
Chain, B. M., and Kaye, P. M., 1986, Processing and presentation by dendritic cells—the role of the lysosome in antigen breakdown, in The Regulation of Gene Expression ( M. Feldmann and A. McMichael, eds.), pp. 207–219, Humana Press, Clifton, NJ.
Chain, B. M., Kaye, P. M., and Feldmann, M., 1986, The cellular pathway of antigen presentation: Biochemical and functional analysis of antigen processing in dendritic cells and macrophages, Immunology
Chain, B. M., Bou-Gharios, G., and Olsen, I., 1989, Endopeptidase activities associated with plasma membrane compartment of an antigen presenting B cell, Clin. Exp. Immunol.
Champion, B. R., Page, K. R., Parish, N., Rayner, D. C., Dawe, K., Biswas-Hughes, G., Cooke, A., Geysen, M., and Roitt, I. M., 1991, Identification of a thyroxine-containing self-epitope of thyroglobulin which triggers thyroid autoreactive T cells, J. Exp. Med.
Davidson, H. W., and Watts, C., 1989, Epitope-directed processing of specific antigen by B lymphocytes, J. Cell Biol.
Davidson, H. W., Reid, P. A., Lanzavecchia, A., and Watts, C., 1991, Processed antigen binds to newly synthesised MHC class II molecules in antigen specific B lymphocytes, Cell
Demotz, S., Grey, H. M., Apella, E., and Sette, A., 1989, Characterisation of a naturally processed MHC class II-restricted T cell determinant of hen egg lysozyme, Nature (London)
Diment, S., 1990, Different roles for thiol and aspartyl proteases in antigen presentation of ovalbumin, J. Immunol.
Diment, S., Leech, M. S., and Stahl, P. D., 1988, Cathepsin D is membrane associated in macrophage endosomes. J. Biol. Chem.
Dunn, K. W., McGraw, T. E., and Maxfield, F. R., 1989, Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome, J. Cell BioL
Eisenlohr, L. C., Gerhard, W., and Hackett, C. J., 1988, Individual class-II restricted antigenic determinants of the same protein exhibit distinct kinetics of appearance and persistence on antigen presentation cells, J. Immunol.
Forquet, F., Caln, V., Trescol-Biemont, M. C., Kanellopoulos, J., Mottez, E., Kourilsky, P., RabourdinCombe, C., and Gerlier, D., 1990, Generation of hen egg lysozyme-specific and major histocompatibility complex class I-restricted cytolytic T lymphocytes: Recognition of cytosolic and secreted antigen expressed by transfected cells, Eur. J. Immunol.
Fox, B. S., Carbone, F. R., Germain, R. N., Paterson, Y., and Schwartz, R. H., 1988, Processing of minimal antigenic peptide alters its interaction with MHC molecules, Nature (London)
Gammon, G., Shastri, N., Cogswell, J., Wilbur, S., Sadegh-Nasseri, S., Krzych, U., Miller, A., and Sercarz, E., 1987, The choice of T cell epitopes utilized on a protein antigen depends on multiple factors distant from as well as at the determinant site, Immunol. Rev.
Germain, R. N., and Hendrix, L. R., 1991, MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding, Nature (London)
Griffiths, G., and Gruenberg, J., 1991, The arguments for preexisting early and late endosomes, Trends Cell Biol. 1: 5–9.
Gruenberg, J., Griffiths, G., and Howell, K. E., 1989, Characterisation of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro, J. Cell Biol.
Guagliardi, L. E., Koppelman, B., Blum, J. S., Marks, M. S., Cresswell, P., and Brodsky, F. M., 1990, Co-localisation of molecules involved in antigen processing and presentation in an early endocytic compartment, Nature (London)
Guidos, C., Wong, M., and Lee, K.-C., 1984, A comparison of the stimulatory activities of lymphoid dendritic cells and macrophages in T proliferative responses to various antigens, J. Immunol.
Harding, C., and Unanue, E., 1989, Antigen processing, and intracellular Ia. Possible roles of endocytosis and protein synthesis in Ia function, J. Immunol.
Harding, C. V., Unanue, E. R., Slot, J. W., Schwartz, A. L., and Geuze, H. J., 1990, Functional and ultrastructural evidence for the intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing, Proc. Natl. Acad. Sci. USA
Hopkins, C. R., Gibson, A., Shipman, M., and Miller, K., 1990, Movement of internalised ligand-receptor complexes along a continuous endosomal reticulum, Nature (London)
Jing, S., Spencer, T., Miller, K., Hopkins, C., and Trowbridge, I. S., 1990, Role for the human transferrin receptor cytoplasmic domain in endocytosis: Localisation of a specific signal sequence for internalisation, J. Cell Biol.
Lanzavecchia, A., 1990, Receptor-mediated antigen uptake and its effects on antigen presentation to class II-restricted T cells, Annu. Rev. Immunol.
Lechler, R. J., Norcross, M. A., and Germain, R. N., 1985, Quantitative studies of antigen presenting cell function using I-A expressing L cells, J. Immunol.
Lee, P., Matsueda, G., and Allen, P., 1988, T cell recognition of fibrinogen, J. Immunol.
Long, E. O., and Jacobson, S., 1989, Pathways of viral antigen processing and presentation to CTL: Defined by the mode of virus entry? Immunol. Today
Lotteau, V., Teyton, L., Peleraux, A., Nilsson, T., Karlsson, L., Schmid, S., Quaranta, V., and Peterson, P. A., 1990, Intracellular transport of class II MHC molecules directed by invariant chain, Nature (London)
Madden, D. R., Gorga, J. C., Strominger, J. L., and Wiley, D. C., 1991, The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation, Nature (London)
Manca, F., Fenoglio, D., Kunkl, A., Cambiaggi, C., Sasso, M., and Celada, F., 1988, Differential activation of T cell clones stimulated by macrophages exposed to antigen complexed with monoclonal antibodies, J. Immunol.
Marcinkiewicz, J., Chain, B. M., Olszowska, E., Olsowski, S., and Zgliczynski, J. M., 1992, Enhancement of immunogenic properties of ovalbumin as a result of its chlorination, Int. J. Biochem., 23: 1393–1395.
Naquet, P., Ellis, J., Singh, B., Hodges, R. S., and Delovich, T. L., 1987, Processing and presentation of insulin. I. Analysis of immunogenic peptides and processing requirements for insulin A loop-specific T cells, J. Immunol.
Neefjes, J. J., Stollorz, V., Peters, P. J., Geuze, H. J., and Ploegh, H. L., 1990, The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route, Cell
Noort, J. M., Boon, J., Van der Drift, A. C. M., Wagenaar, J. P., Boots, A. M. H., and Boog, C. J. P., 1991, Antigen processing by endosomal proteases determines which sites of sperm-whale myoglobin are eventually recognised by T cells, Eur. J. Immunol.
Parham, P., 1990, Antigen processing: Transporters of delight, Nature (London) 348: 674–675.
Peters, P. J., Neefjes, J. J., Oorschot, V., Ploegh, H. L., and Geuze, H. J., 1991, Segregation of MHC class II
molecules from class I molecules in the Golgi complex for transport to lysosomal compartments, Nature (London)
Peterson, M., and Miller, J., 1990, Invariant chain influences the immunological recognition of MHC class II molecules, Nature (London)
Puri, J., and Factorovich, Y., 1988, Selective inhibition of antigen presentation to cloned cells by protease inhibitors, J. Immunol.
Puri, J., Lonai, P., and Friedman, V., 1986, Antigen–la interaction and the proteolytic processing of an antigen: The structure of the antigen determines its restriction to the A or E molecule of the MHC, Eur. J. Immunol.
Régnier-Vigouroux, A., El-Aych, M., Defendini, M.-L., Graniel, C., and Pierres, M., 1988, Processing by accessory cells for presentation to murine T cells ofapamin, a disulfide bonded 18 amino-acid peptide, J. Immunol.
Reid, P. A., and Watts, C., 1990, Cycling of cell-surface MHC glycoproteins through primaquine-sensitive intracellular compartments, Nature (London)
Reyes, V. E., Lu, S., and Humphreys, R. E., 1991, Cathepsin B cleavage of Ii from class 11 MHC a and (3 chains, J. Immunol.
Robertson, M., 1991, Antigen processing—proteasomes in the pathway, Nature (London) 353:300–301. Roche, P. A., and Cresswell, P., 1990, Invariant chain association with HLA-DR molecules inhibits immunogenic binding, Nature (London)
Romani, N. S., Koide, M., Crowley, M., Witmer-Pack, A. M., Livingstone, C., Fathman, C. G., Inaba, K., and Steinman, R. M., 1989, Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature epidermal Langerhans cells, J. Exp. Med.
Roosnek, E., Demotz, S., Corradin, G., and Lanzavecchia, A., 1988, Kinetics of MHC-antigen complex formation on antigen presenting cells, J. Immunol.
Rötzschke, O., Falk, K., Waliny, H.-J., Faath, S., and Rammensee, H.-G., 1990, Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y, Science
Rudensky, A. Y., Preston-Hurlburt, P., Hong, S.-C., Barlow, A., and Janeway, C. A., Jr., 1991, Sequence analysis of peptides bound to MHC class II molecules, Nature (London)
Shaw, M.-A., and Chain, B. M., 1989, A cell-free model system for the study of antigen processing, Int. Immunol.
Steinman, R. M., 1991, The dendritic cell system and its role in immunogenicity, Annu. Rev. Immunol.
Streicher, H. Z., Berkower, I. J., Busch, M., Gurd, F. R. N., and Berzofsky, J. A., 1984, Antigen conformation determined processing requirements for T cell activation, Proc. Natl. Acad. Sci. USA
Takahashi, H., Cease, K. B., and Berzofsky, J. A., 1989, Identification of proteases that process distinct epitopes on the same protein, J. Immunol.
Ukkonen, P., Lewis, V., Marsh, M., Helenius, A., and Mellman, I., 1985, Transport of macrophage Fc receptor and Fc receptor-bound ligands to lysosomes, J. Exp. Med.
Vanbuskirk, A., Crump, B. L., Margiolash, E., and Pierce, S., 1989, A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family, J. Exp. Med.
Yewdell, J. W., and Bennink, J. R., 1990, The binary logic of antigen processing and presentation to T cells, Cell
Yoshikawa, M., Watanabe, M., and Hozumi, N., 1987, Analysis of proteolytic processing during specific antigen presentation, Cell. Immunol.
Ziegler, H. K., and Unanue, E. R., 1982, Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells, Proc. Natl. Acad. Sci. USA