Iron-Mediated Oxidative Stress and Erythrocytes

  • Catherine Rice-Evans
Part of the Blood Cell Biochemistry book series (BLBI, volume 1)


Iron in its labile, chelatable form has been implicated in the generation of radical species such as the hydroxyl radical, ferryl species [an Fe(IV)-oxygen complex], perferryl (Fe2+ −O2 ↔ Fe3+ −O 2 ∙), and Fe2+ /Fe3+ /O2 complexes (for reviews see Halliwell and Gutteridge, 1986; Czapski and Goldstein, 1986; Aust and White, 1986; Aust and Minotti, 1987; Gutteridge and Halliwell, 1989) and in the propagation of oxidative events.


Lipid Peroxidation Sickle Cell Iron Overload Lipid Hydroperoxide Iron Complex 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Catherine Rice-Evans
    • 1
  1. 1.Department of Biochemistry and ChemistryRoyal Free Hospital School of MedicineLondonEngland

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