Abstract
The principal mechanisms of regulation which apply to both primary and secondary metabolite biosynthesis are the repression of enzyme synthesis and the inhibition of enzyme activity. However, the fact that these operate in the control of secondary metabolite biosynthesis has only recently been well accepted. Some of these mechanisms are specific for antibiotic production but, remembering that secondary metabolism is a form of differentiation, it is not surprising that its regulation often falls under more general systems of control governing other forms of differentiation, such as the sporulation process or the formation of aerial mycelium.
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© 1993 Springer Science+Business Media New York
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Lancini, G., Lorenzetti, R. (1993). Regulation of Antibiotic Biosynthesis. In: Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9522-6_5
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DOI: https://doi.org/10.1007/978-1-4757-9522-6_5
Publisher Name: Springer, Boston, MA
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