Biologically Active Polyphosphate and Polyphosphonate Esters — Nucleic Acid Analogs

  • Charles E. CarraherJr.
  • Daniel S. Powers
  • Bhoomin Pandya


A number of polyphosphate and polyphosphonate esters derived from biologically active diols were synthesized. The diols included androstendiol, amcinafal, dienestrol, 5-iodo2-deoxyuridine and diethylstilbestrol. The products showed a wide range of activities towards the bacteria tested and generally decent to good activity towards the cancer cell lines tested.


Normal Flora Weight Average Molecular Weight Baby Hamster Kidney DMSO Control Alcaligenes Faecalis 
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Charles E. CarraherJr.
  • Daniel S. Powers
    • 1
    • 2
  • Bhoomin Pandya
    • 1
    • 2
  1. 1.Department of ChemistryFlorida Atlantic UniversityBoca RatonUSA
  2. 2.Department of ChemistryWright State UniversityDaytonUSA

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