Skip to main content

Abstract

Results of thermal analyses of select diagnostic enzymes and their utility in determining stability of dry chemistries have been presented in this paper. An enzymatic compound consisting of glucose oxidase, peroxidase, tetramethyl benzidine indicator, alkylbenzene sulfonate and polyhydroxyethyl methacrylate was prepared and compression molded. Strips molded up to 150°C gave good glucose response. During molding the redox centers of the enzyme are not disturbed whereas the bulk of the enzyme, polymeric in composition, blends with PHEMA producing the unusual stability. There is a distinct possibility that a reaction injection molding (RIM) composition and processing can be developed for making dry chemistries.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. B. Walter, Anal. Chem., 55, 449A (1983).

    Article  Google Scholar 

  2. A. H. Free and H. M. Free, Lab. Med., 15, 1595 (1984).

    Google Scholar 

  3. T. K. Mayer and N. P. Kubasik, Lab. Mgmt., 43 (April 1986).

    Google Scholar 

  4. J. A. Jackson and M. E. Conrad, Am. Clin. Products Rev., 6, 10 (1987)

    Google Scholar 

  5. A. F. Azhar, A. D. Burke, J. E. DuBois and A. M. Usmani, Polymer Mat. Sci. Eng., 59, 1539 (1988).

    Google Scholar 

  6. E. Diebold, M. Rapkin and A. Usmani, ChemTech, 21, 462 (1991).

    CAS  Google Scholar 

  7. M. T. Skarstedt and A. M. Usmani, Polymer News, 14, 38 (1989).

    CAS  Google Scholar 

  8. R. S. Campbell and C. P. Price, J. Intern Fed. Clin. Chem., 3, 204 (1991).

    CAS  Google Scholar 

  9. A. Azhar, A. Burke, J. DuBois and A. Usmani, Polymer Mat. Sci. Eng., 66 (1992).

    Google Scholar 

  10. A. Azhar, A. Burke, J. DuBois and A. Usmani, in: “Progress in Biomedical Polymers, C. G. Gebelein, Ed, Plenum, New York, 1990, pp. 149–156.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media New York

About this chapter

Cite this chapter

Kennamer, J.E., Burke, A.D., Usmani, A.M. (1994). Moldable Dry Chemistry. In: Gebelein, C.G., Carraher, C.E. (eds) Biotechnology and Bioactive Polymers. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9519-6_19

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-9519-6_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9521-9

  • Online ISBN: 978-1-4757-9519-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics