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Cell Adhesive Properties of Bioelastic Materials Containing Cell Attachment Sequences

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Biotechnology and Bioactive Polymers

Abstract

The biocompatibility, conformational and inverse temperature transition properties of poly(Vall-Pro2-Gly3-Va14- Gly5), i.e., poly(VPGVG), and its 7-irradiation crosslinked matrix and the poly(VPGVG)-derived hydrophobicity scale are noted. Also noted are the capacities of varying the bioactive role of bioelastic materials; that is, the bioelastic materials can be designed (1) to exhibit a range of elastic moduli, (2) to exhibit different rates of degradation, (3) for various modes of drug release, (4) to perform numerous free energy transductions, (5) to contain functional enzyme sites, and (6) to contain functional cell attachment sequences that promote growth to confluence.

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References

  1. D. W. Urry, T. M. Parker, A. Nicol, A. Pattanaik, D. S. Minehan, D. C. Gowda, C. Morrow and D. T. McPherson, Am. Chem. Soc., Div. Polym. Mater.: Sci. and Eng., 66, 399–402 (1992).

    CAS  Google Scholar 

  2. L. Sandberg, J. Leslie, C. Leach, V. Torres, A. Smith and D. Smith, Pathol. Biol., 33, 266–274 (1985).

    PubMed  CAS  Google Scholar 

  3. H. Yeh, N. Ornstein-Goldstein, Z. Indik, P. Sheppard, N. Anderson, J. Rosenbloom, G. Cicila, K. Yoon and J. Rosenbloom, Collagen and Related Research, 7, 235 (1987).

    Article  PubMed  CAS  Google Scholar 

  4. L. B. Sandberg, N. T. Soskel and J. B. Leslie, N. Engl. J. Med., 304, 566–579 (1981).

    Article  PubMed  CAS  Google Scholar 

  5. D. W. Urry, T. M. Parker, M. C. Reid and D. C. Gowda, J. Bioactive Compatible Poly., 6, 263–282 (1991).

    Article  CAS  Google Scholar 

  6. D. W. Urry, in: “Molecular Conformation and Biological Interactions, P. Balaram and S. Ramaseshan, Eds., Indian Acad. of Sci., Bangalore, India, 1991, pp. 555–583.

    Google Scholar 

  7. D. W. Urry, D. C. Gowda, T. M. Parker, C.-H. Luan, M. C. Reid, C. M. Harris, A. Pattanaik and R. D. Harris, Biopolymers, 32, pp 1243–1250 (1992).

    Article  PubMed  CAS  Google Scholar 

  8. D. W. Urry, Prog. Biophys. Molec. Biol., 57, 23–57 (1992).

    Article  CAS  Google Scholar 

  9. D. W. Urry, Mat. Res. Soc. Symp. Proc., 174, 243–250 (1990).

    Article  CAS  Google Scholar 

  10. D. W. Urry, D. C. Gowda, C. Harris, R. D. Harris and B. A. Cox, Poly. Preprints Am. Chem. Soc. Polym. Chem. Div., 32, pp 84–85 (1992).

    Google Scholar 

  11. D. W. Urry, in: “Cosmetic and Pharmaceutical Applications of Polymers, C. G. Gebelein, T. C. Cheng and V. C. Yang, Eds., Plenum Press, New York, 1991, 181–192.

    Google Scholar 

  12. H. M. Kagan, L. Tseng, P. C. Trackman, K. Okamoto, R. S. Rapaka and

    Google Scholar 

  13. D. W. Urry, J. Biol. Chem., 255, 3656–3659 (1980).

    PubMed  Google Scholar 

  14. D. W. Urry, H. Sugano, K. U. Prasad, M. M. Long and R. S. Bhatnagar, Biochem. Biophys. Res. Commun., 90, 194–198 (1979).

    Article  CAS  Google Scholar 

  15. A. Pattanaik, D. C. Gowda and D. W. Urry, Biochem. Biophys. res. Comm., 178, 539–545 (1991).

    CAS  Google Scholar 

  16. A. Nicol, D. C. Gowda and D. W. Urry, Biomed. Mater. Res., 26, 393413 (1992).

    Google Scholar 

  17. M. M. Long, V. J. King, K. U. Prasad, B. A. Freeman and D. W. urry, J. Cell. Phys., 140, 512–518 (1989).

    Article  CAS  Google Scholar 

  18. M. D. Pierschbacher and E. Ruoslahti, Nature, 309, 30 (1984).

    Article  PubMed  CAS  Google Scholar 

  19. D. W. Urry, J. Protein Chem., 7, 1 (1988).

    Article  PubMed  CAS  Google Scholar 

  20. D. W. Urry, B. Haynes, M. Zhang, R. D. Harris and K. U. Prasad, Proc. Natl. Acad. Sci. USA, 85, 3407 (1988).

    Article  CAS  Google Scholar 

  21. K. U. Prasad, M. A. Iqbal and D. W. Urry, Int. J. Pept. Protein Res., 25, 408 (1985).

    Article  PubMed  CAS  Google Scholar 

  22. D. W. Urry and K. U. Prasad, in: “Biocompatibility of Tissue Analogues, D. F. Williams, Ed., CRC Press, Inc., Boca Raton, Florida, 89–116 (1985).

    Google Scholar 

  23. R. B. Merrifield, Biochemistry, 3, 1385–1390 (1964).

    Article  PubMed  CAS  Google Scholar 

  24. M. A. Barton, R. U. Lemieux and J. Y. Savoie, J. Am. Chem. Soc., 95, 4501–4506 (1973).

    Article  PubMed  CAS  Google Scholar 

  25. J. P. Tam, W. F. Heath and R. B. Merrifield, J. Am. Chem. Soc., 105, 6442–6455 (1973).

    Article  Google Scholar 

  26. M. J. Humphries, S. K. Akiyama, A. Komoriya, K. Olden and K. M. Yamada, J. Cell. Biol., 103, 2637 (1986).

    Article  PubMed  CAS  Google Scholar 

  27. J. A. Hubbell, S. P. Massia, N. P. Desai and P. D. Drumheller, Biotechnology, 9, 568 (1991).

    Article  PubMed  CAS  Google Scholar 

  28. A. P. Mould, A. Komoriya, K. M. Yamada and M. J. Humphries, J. Biol. Chem., 266, 3579 (1991).

    Google Scholar 

  29. M. D. Pierschbacher and E. Ruoslahti, J. Biol. Chem., 262, 17294 (1987).

    PubMed  CAS  Google Scholar 

  30. S. Suzuki, A. Oldberg, E. G. Hayman, M. D. Pierschbacher and E. Ruoslahti, EMBO J., 4, 2519 (1985).

    PubMed  CAS  Google Scholar 

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© 1994 Springer Science+Business Media New York

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Nicol, A., Gowda, D.C., Parker, T.M., Urry, D.W. (1994). Cell Adhesive Properties of Bioelastic Materials Containing Cell Attachment Sequences. In: Gebelein, C.G., Carraher, C.E. (eds) Biotechnology and Bioactive Polymers. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9519-6_10

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  • DOI: https://doi.org/10.1007/978-1-4757-9519-6_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9521-9

  • Online ISBN: 978-1-4757-9519-6

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