Biolized Material for Cardiac Prosthesis

  • Shun Murabayashi
  • Yukihiko Nose
Part of the Polymer Science and Technology book series (POLS, volume 14)


It has been well documented that most artificial materials, whether hydrophilic, hydrophobic, made electroconductive by the dispersion of conductive particles in it, smooth, rough or heparinized, were covered with protein immediately following implantation into the cardiovascular system (1,2). Regardless of this protein coating, some of the materials had higher thromboresistance than others. Many theories have been proposed to explain these thromboresistant properties, but a definitive answer to these questions would be premature at this time. We have also found that not every protein surface shows thromboresistance; however, when the protein surface was treated with an aldehyde or heat, it resulted in a reproducibly improved thromboresistant surface.


Natural Rubber Natural Tissue Biological Component Artificial Heart Blood Compatibility 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Shun Murabayashi
    • 1
  • Yukihiko Nose
    • 1
  1. 1.Department of Artificial OrgansCleveland ClinicClevelandUSA

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