Abstract
It has been well documented that most artificial materials, whether hydrophilic, hydrophobic, made electroconductive by the dispersion of conductive particles in it, smooth, rough or heparinized, were covered with protein immediately following implantation into the cardiovascular system (1,2). Regardless of this protein coating, some of the materials had higher thromboresistance than others. Many theories have been proposed to explain these thromboresistant properties, but a definitive answer to these questions would be premature at this time. We have also found that not every protein surface shows thromboresistance; however, when the protein surface was treated with an aldehyde or heat, it resulted in a reproducibly improved thromboresistant surface.
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References
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Murabayashi, S., Nose, Y. (1981). Biolized Material for Cardiac Prosthesis. In: Gebelein, C.G., Koblitz, F.F. (eds) Biomedical and Dental Applications of Polymers. Polymer Science and Technology, vol 14. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9510-3_9
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DOI: https://doi.org/10.1007/978-1-4757-9510-3_9
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