Elastomeric Vascular Prostheses

  • Donald J. Lyman
  • Kenneth B. Seifert
  • Helene Knowlton
  • Dominic AlboJr.
Part of the Polymer Science and Technology book series (POLS, volume 14)


We have been investigating the effect of chemical structure and surface properties of synthetic polymers on the coagulation of blood. The ultimate goal of these studies is the development of satisfactory prostheses to replace damaged veins, bypass obstructed arteries of small diameter (less than 6 mm) and for use in aortocoronary surgery. Currently, the surgeon is forced to use autogenous tissue such as the saphenous vein in these situations because of the lack of good synthetic polymer prostheses. Although the results using autogenous saphenous veins are very good, this method has certain disadvantages. Some patients (10 to 25%) do not have satisfactory veins either because of prior removal, disease (varicosities), or because the vein is of inadequate size. Even with patients having satisfactory veins, one has to contend with the problem of limited quantity and a significant increase in operating time. The presently available synthetic polymer prostheses are made from relatively thrombogenic polymers (Teflon and Dacron). These materials show patency rates of less than 50% at diameters smaller than 6 mm. Therefore, the development of a successful, small diameter synthetic polymer prosthesis is of utmost importance to both the patient and the surgeon.


Latex Rubber Vascular Prosthesis Natural Artery Elastic Index Autogenous Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1981

Authors and Affiliations

  • Donald J. Lyman
    • 1
  • Kenneth B. Seifert
    • 1
  • Helene Knowlton
    • 1
  • Dominic AlboJr.
    • 1
  1. 1.Department of Materials Science and Engineering and Department of SurgeryUniversity of UtahSalt Lake CityUSA

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